Colorectal cancer (CRC) remains one of the most common types of cancer globally, affecting both men and women. In recent years, however, there has been an alarming shift in the demographics of those diagnosed. Early in 2023, the American Cancer Society (ACS) revealed that 20% of colorectal cancer diagnoses in 2019 occurred in individuals under the age of 55, nearly double the rate seen in 1995.
As with many other cancers, lifestyle factors—including diet—can play a significant role in the development and prevention of colorectal cancer. While genetics and environmental factors are beyond our control, adopting a healthy diet can reduce the risk of developing CRC.
In this article, we’ll explore foods that may help prevent colorectal cancer and how these choices can support overall digestive health.
The Link Between Diet and Colorectal Cancer
Dietary habits influence the health of the colon and rectum in various ways. Consuming nutrient-rich foods, fiber, and antioxidant-packed fruits and vegetables helps maintain a healthy gastrointestinal system. On the flip side, poor dietary choices such as excessive consumption of red and processed meats, low fiber intake, and high-fat diets can contribute to the development of colorectal cancer.
Colorectal cancer often begins with the growth of polyps, which are small clumps of cells that can develop into cancer over time. Many of the dietary recommendations to prevent colorectal cancer are focused on inhibiting the formation of polyps and reducing inflammation in the colon. Let’s dive deeper into some of the best foods that can help lower the risk of this disease.
1. Fruits and Vegetables: A Rich Source of Antioxidants and Fiber

Fruits and vegetables are packed with essential nutrients, including vitamins, minerals, antioxidants, and fiber. These nutrients work together to promote overall health and reduce the risk of cancer, including colorectal cancer.
Fiber-Rich Vegetables
Fiber is a key nutrient in reducing the risk of colorectal cancer. A diet high in fiber can prevent constipation, improve digestion, and reduce the time carcinogens spend in the colon. High-fiber vegetables such as broccoli, Brussels sprouts, kale, spinach, carrots, and sweet potatoes are excellent choices for cancer prevention. Cruciferous vegetables like broccoli and cauliflower are particularly notable due to their high content of sulforaphane, a compound shown to have anti-cancer properties.
Antioxidants in Fruits
Fruits such as berries, oranges, apples, and grapes are rich in antioxidants, which help protect the body from oxidative stress that can lead to cancer. Berries like blueberries, strawberries, and raspberries are high in anthocyanins, powerful antioxidants that protect the cells in the colon from damage. Citrus fruits like oranges, lemons, and grapefruits contain vitamin C, another antioxidant that can reduce the risk of cancer by neutralizing harmful free radicals in the body.
2. Whole Grains: The Power of Fiber and Phytochemicals
Whole grains, such as brown rice, quinoa, oats, and whole wheat, are excellent sources of dietary fiber. The fiber in whole grains helps keep the digestive system functioning optimally by promoting regular bowel movements and preventing constipation. Fiber also binds to bile acids in the gut and helps expel them from the body, which may reduce the risk of colorectal cancer.
In addition to fiber, whole grains contain important nutrients such as B vitamins, magnesium, and phytochemicals. These compounds have been shown to possess anti-inflammatory and antioxidant properties, which can help reduce the risk of cancer by promoting cellular health.
3. Legumes: Beans, Lentils, and Peas
Legumes, including beans, lentils, chickpeas, and peas, are rich in fiber, protein, vitamins, and minerals. These plant-based foods help maintain a healthy digestive system, and their high fiber content promotes regular bowel movements. Additionally, legumes contain resistant starch, which is fermented by beneficial bacteria in the gut to produce short-chain fatty acids like butyrate. Butyrate has been shown to inhibit the growth of cancer cells and reduce inflammation in the colon.
A diet rich in legumes is particularly beneficial for those seeking plant-based alternatives to meat. Studies have suggested that populations with higher intakes of legumes have a lower risk of colorectal cancer compared to those with diets high in animal products.
4. Nuts and Seeds: Healthy Fats and Fiber
Nuts and seeds, such as almonds, walnuts, flaxseeds, chia seeds, and sunflower seeds, provide a good source of healthy fats, fiber, and important vitamins. Omega-3 fatty acids, found in walnuts and flaxseeds, have anti-inflammatory properties that may help prevent colorectal cancer by reducing inflammation in the colon.
In addition, the fiber in nuts and seeds supports gut health by improving bowel regularity and providing nourishment for beneficial gut bacteria. Incorporating a variety of nuts and seeds into your diet can improve overall digestive function and provide cancer-fighting nutrients.
5. Fish: Omega-3 Fatty Acids and Antioxidants

Fatty fish, such as salmon, mackerel, sardines, and tuna, are rich in omega-3 fatty acids, which have been shown to have anti-inflammatory and anti-cancer properties. Omega-3 fatty acids may help reduce the formation of polyps in the colon and may also play a role in slowing the progression of colorectal cancer. Additionally, fish contains vitamin D, which helps maintain proper cellular function and is believed to have a protective effect against certain cancers, including colorectal cancer.
The anti-inflammatory effects of omega-3s can also reduce oxidative stress and chronic inflammation in the digestive tract, both of which contribute to cancer development. Aim to include fatty fish in your diet two to three times a week for maximum benefit.
6. Turmeric: The Cancer-Fighting Spice
Turmeric, the bright yellow spice commonly used in Indian cuisine, contains a powerful compound called curcumin. Curcumin has been studied extensively for its anti-inflammatory and antioxidant properties, which can help reduce the risk of colorectal cancer. Research has shown that curcumin can inhibit the growth of cancer cells, promote apoptosis (programmed cell death) in cancer cells, and prevent the formation of tumors.
Incorporating turmeric into your diet is simple, as it can be added to curries, soups, smoothies, and teas. For better absorption, combine turmeric with black pepper, which contains piperine, a compound that enhances curcumin’s bioavailability.
7. Olive Oil: A Heart-Healthy Fat with Cancer Protection
Olive oil, particularly extra virgin olive oil, is a key component of the Mediterranean diet and is associated with numerous health benefits, including a reduced risk of colorectal cancer. Olive oil contains monounsaturated fats, which help reduce inflammation in the body. It also contains polyphenols, which are plant compounds that have antioxidant and anti-cancer properties.
Studies suggest that incorporating olive oil into your diet, replacing other fats like butter or vegetable oils, may help reduce the risk of colorectal cancer by promoting healthy digestion and protecting cells from oxidative damage.
8. Garlic and Onions: Natural Cancer Fighters
Garlic and onions are members of the allium family of vegetables, and both have been linked to a reduced risk of colorectal cancer. Garlic, in particular, contains sulfur compounds such as allicin, which have been shown to inhibit the growth of cancer cells and prevent the formation of tumors in the colon. These compounds also help reduce inflammation in the body and promote the elimination of harmful substances from the digestive system.
Both garlic and onions are versatile ingredients that can be added to salads, soups, sauces, and roasted dishes. To maximize their cancer-fighting properties, try consuming them raw or lightly cooked, as high heat can reduce the potency of their beneficial compounds.
9. Fermented Foods: Beneficial Bacteria for Gut Health
Fermented foods such as yogurt, kefir, kimchi, sauerkraut, miso, and tempeh contain beneficial bacteria (probiotics) that support gut health and reduce inflammation. A healthy gut microbiome plays an essential role in maintaining a healthy colon and reducing the risk of colorectal cancer. Probiotics help balance the gut flora, improve digestion, and may help inhibit the growth of harmful bacteria that could contribute to cancer development.
Fermented foods are easy to incorporate into your diet and provide a natural source of probiotics to improve gut health.
A Healthy Diet as a Key Defense Against Colorectal Cancer
While no single food can guarantee protection from colorectal cancer, a well-balanced diet that emphasizes fiber-rich fruits, vegetables, whole grains, legumes, healthy fats, and fermented foods can play a key role in reducing the risk. By consuming a variety of nutrient-dense, anti-inflammatory foods, you can promote a healthy digestive system, support cellular health, and lower your risk of colorectal cancer.
In addition to a healthy diet, it is essential to maintain a healthy lifestyle by staying physically active, managing stress, avoiding excessive alcohol consumption, and quitting smoking. Regular screenings and early detection also play a vital role in identifying colorectal cancer in its early stages when treatment is most effective.
Ultimately, a proactive approach to nutrition, alongside regular check-ups, can help protect your health and prevent colorectal cancer.